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Home / Sexually transmitted infections (STIs) / Chlamydia / Doxycycline Capsules

Doxycycline Capsules

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What is Doxycycline?

Doxycycline is a tetracycline antibiotic, a versatile medicine used to treat a wide range of conditions. Mostly, you will be prescribed Doxycycline for malaria, bacterial pneumonia, and certain STIs like chlamydia and syphilis.

It was first developed in the early 1960s by Pfizer, and has since become one of the most widely used antibiotic medications. When taken daily, it stops bacterial cells from reproducing and clears your body of harmful infections.

euroClinix prescribes this treatment specifically for chlamydia, malaria , ureaplasma urealyticum , and non-specific urethritis

What is Doxycycline used for?

This medicine is used to treat a number of conditions, including:

To find out more about what Doxycycline treats, consult the patient information leaflet sent with your order.

How does Doxycycline work?

Doxycycline belongs to a group of antibiotics called tetracyclines. These work by binding to harmful bacteria and preventing them from producing essential proteins. While this doesn’t kill bacteria directly, it stops them from multiplying, allowing your body’s immune system to fight off and heal infection.

It is effective against a wide range of bacteria, meaning it can be used to treat multiple bacterial conditions, like malaria and chlamydia.

In addition to this, it has an anti-inflammatory effect, so it is licensed to treat skin conditions like acne and rosacea.

It must be taken daily to ensure a steady supply of the medicine in your bloodstream. After your prescribed course is complete, your infection should be cleared. Stopping before this point risks the infection coming back, so you must take it for the full course.

What are the benefits of Doxycycline?

Taking Doxycycline for your condition can have several health benefits:

Key benefits of Doxycycline

multiple conditions Effective against multiple conditions

it can treat STIs, skin conditions, and many other infections.

Dual action Dual-action treatment

anti-inflammatory properties mean it can also treat skin conditions

Malaria prevention Malaria prevention

taking it daily can prevent the onset of malaria.

Antibiotic Broad-spectrum antibiotic

effective against a wide range of bacteria.

How effective is Doxycycline?

Doxycycline has been found in clinical trials to be an effective treatment for many conditions. Here are the key findings:

Doxycycline Clinical Studies Results

Chlamydia Treatment study

Participants:
416 women

Duration:
4 weeks

Dosing:
100 mg twice daily


Effectiveness rate

Doxycycline - Rectal

95.5%

Doxycycline - vaginal

95.4%

Azithromycin - rectal

78.5%

Azithromycin - vaginal

93.5%

Malaria prevention study

Participants:
12 patients

Duration:
3 days before, and 6 days after exposure

Dosing:
100 mg twice daily


Effectiveness rate

Prevention rate

67%

Non-specific urethritis study

Participants:
90 men

Duration:
10 days

Dosing:
100 mg twice daily


Effectiveness rate

Patients with pathogens

92%

Patients without pathogens

85%

The effectiveness of this medicine depends on individual factors such as age, overall health, and the presence of other medical conditions. Consult your doctor for personalised advice.

Who can and cannot take Doxycycline?

This treatment may not be suitable for everyone. Disclose your health status with our medical team during your consultation to ensure safety.

Who can take it?

Doxycycline 100 mg capsules are generally safe for most people. While most people take Doxycycline for chlamydia, it can also be prescribed for adults who suffer from:

Please note that overuse of antibiotics may result in you developing antibiotic resistance. Let your doctor know if you have taken this treatment before.

Who cannot take it?

You cannot take this medication:

  • If you are allergic to doxycycline hyclate or any other ingredient found in this medicine
  • If you are allergic to any other tetracycline antibiotic
  • During periods of tooth development (e.g. pregnancy, infancy)

Cautions

In addition to these contraindications, there are some circumstances where the safety of this treatment will need to be determined by our medical team. Let our doctors know if any of the following apply to you:

  • You are likely to be exposed to strong sunlight or UV light - your skin may be more sensitive to sunburn.
  • Kidney or liver problems
  • Myasthenia gravis (a disease that causes unusual tiredness and weakness)
  • Porphyria (a rare blood disease)
  • Systemic lupus erythematosus (an allergic skin condition causing joint pain, skin rashes and fever)
  • Syphilis
  • Diarrhoea as a result of antibiotic use

Please disclose your health status during your online consultation with euroClinix. Our medical team will evaluate whether this treatment is suitable for you and may adjust your medications if needed.

How do I take Doxycycline capsules?

To take Doxycycline 100 mg capsules correctly, follow the dosage and treatment course our medical team prescribes. This ensures the drug's effectiveness and helps avoid side effects.

When taking your capsules:

  • Take with a glass of water
  • Avoid lying down for at least 30 minutes after taking it
  • For acne, take with food or a drink
  • For infections, take with or without food

Dosage

At euroClinix, Doxycycline capsules are only available in one dose: 100 mg.

However, the usual recommended dose varies depending on your condition. Consult this helpful table for the average recommended dose:

Doxycycline dosage schedule
Condition* Dosage For how long?
STIs 100 mg twice daily 7-10 days
Other infections 200 mg on the first day, then 100 mg once daily Duration varies depending on the condition treated
Malaria prevention 100 mg daily 1-2 days before travelling to a malaria-prone area until 4 weeks after returning
Acne 50 mg daily 6-12 weeks
Primary and secondary syphilis 200 mg twice daily 2 weeks
Fevers associated with louse or tick bites 100-200 mg Single dose

*At euroClinix, we only prescribe this treatment for malaria, chlamydia, ureaplasma urealyticum, and non-specific urethritis.

NOTE: This is not an exhaustive list of the conditions treated by Doxycycline.

When should I take it?

You should take your capsules at the same time every day for peak effectiveness. This ensures there is a steady supply of the medicine in your bloodstream.

What if I miss a dose?

If you forget to take a capsule and it is the same day, take it as soon as you remember and take your next dose at the regular time.

If it is already the next day, skip the missed dose and take the next one at the regular time.

How long does Doxycycline take to work?

You should begin to feel better a few days after starting treatment, but you must complete the full course to avoid your infection coming back. The length of treatment depends on your condition.

What should I do while taking Doxycycline?

Making certain lifestyle changes can complement your treatment and support overall health. Consider the following when taking your medication.

Lifestyle guide for Doxycycline

Follow these guidelines to maximise effectiveness and minimise side effects

Stay hydrated Stay hydrated.

Drink plenty of water to prevent throat or stomach irritation.

Avoid dairy Avoid dairy.

Dairy products can reduce the effectiveness of antibiotics like Doxycycline. Avoid them for two hours after taking your capsules.

Maintain a healthy diet Maintain a healthy diet

A healthy diet can support your immune system. Eat more citrus fruits, garlic, and spinach in your meals.

Don't lie down Don’t lie down

Stay upright for at least 30 minutes to prevent throat irritation.

Practice safe sex Practice safe sex

If treating an STI, avoid sexual contact until your treatment is complete.

Always follow your healthcare provider’s specific instructions and report any concerning side effects

Adding probiotics to your diet while taking doxycycline can help support gut health and may reduce the risk of antibiotic-associated side effects, such as diarrhea. Foods like kimchi, sauerkraut, and pickled vegetables, or high-quality probiotic supplements, are great options to consider. In order for the probiotics to be effective, take them two hours away from the medication.

Silvia Fonda Nutritionist

What are the Doxycycline side effects?

As with all prescription medications, this treatment may produce side effects.

If you notice any of the following side effects, stop treatment and seek immediate medical help:

Serious side effects
  • Sudden wheeziness, chest pain, fever, swelling of the face - could be a sign of an allergic reaction.
  • Upset stomach, loss of appetite, and severe, persistent or bloody diarrhoea - could be a sign of serious bowel inflammation.
  • Fever, swollen lymph nodes, or a skin rash - could be symptoms of DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms).
  • A very severe headache, which may be associated with visual disturbances - could lead to permanent vision loss.
Common side effects (may affect up to 1 in 10 people)
  • Feeling or being sick
  • Worsening of systemic lupus erythematosus (an allergic skin condition causing joint pain, skin rashes and fever)
  • Pericarditis (inflammation affecting the heart)
Uncommon side effects (may affect up to 1 in 100 people)
  • Heartburn
  • Vaginal infection
Rare side effects (may affect up to 1 in 1,000 people)
  • Anxiety
  • Difficulty swallowing
  • Skin reddening (flushing)
  • A ringing or buzzing in the ear
  • Soreness and itching of the rectal and/or genital area
  • Bowel inflammation
  • Increased pressure in the skull
  • Inflammation and damage to the liver
  • Discolouration of the thyroid tissue
  • Loosening of the nail after sun exposure
  • Increased level of urea (waste product) in the blood
  • Yellow skin and eyes (jaundice)
  • Upset stomach, loss of appetite, diarrhoea

How to manage side effects

Most side effects, such as headaches or nausea, are usually temporary and resolve on their own. To help manage these effects, drink plenty of water, avoid lying down immediately after taking Doxycycline, and limit alcohol intake.

If you experience muscle pain or fatigue, rest as much as possible and avoid strenuous physical activity until the symptoms subside.

Taking doxycycline with food or a full glass of water can help reduce nausea and prevent irritation of the esophagus. To maximize absorption, avoid taking it with dairy products or antacids. If symptoms persist or side effects seem serious, consult your doctor or pharmacist for medical advice.

Dr. Caroline Fontana Lead Prescribing Doctor

Serious side effects of Doxycycline: take action

Stop treatment immediately and seek medical help if you experience:

  • Allergic reaction - difficulty breathing, chest pain, facial swelling.
  • Stomach problems - upset stomach, loss of appetite, severe diarrhoea.
  • A serious drug reaction - high fever, swollen glands, widespread rash.
  • Permanent vision loss - severe headache with blurry or lost vision.
  • Skin reactions - severe, painful blisters with peeling skin.

What to do: stop taking your medication and contact your doctor or visit the ER immediately. Always act quickly when symptoms appear.

For more detailed information, please refer to the patient information leaflet.

What interacts with Doxycycline?

Some medications may interfere with how Doxycycline works or increase the risk of side effects. Tell your doctor about any medications you take in your consultation, including the following:

  • Antacids (heartburn medication) - can reduce drug absorption.
  • Penicillin (antibiotic) - Doxycycline may interfere with Penicillin’s effectiveness.
  • Blood thinning medications (e.g. Warfarin) - taking these together can increase blood clotting time.
  • Epilepsy medications (e.g. Carbamazepine, Phenytoin) - can shorten this medication’s half-life.
  • Oral contraceptives - taking these together may increase the risk of pregnancy or breakthrough bleeding.
  • Ciclosporin (prevents organ rejection) - can raise Ciclosporin levels in the blood.
  • Methoxyflurane (inhaled pain reliever) - increases the risk of serious kidney damage.
  • Isotretinoin & systemic retinoids (vitamin A-derived skin treatments) - increases the risk of pressure in the brain.

This list does not cover all possible interactions. For a comprehensive list, please visit the interactions checker on the BNF website.

What safety advice should be followed while taking Doxycycline?

Category Safety Advice
Alcohol Avoid Alcohol can reduce the effectiveness of this medicine and should be avoided.
Pregnancy Unsafe This medicine may affect the development of the baby and should be avoided when pregnant.
Breastfeeding Unsafe The active ingredient passes into breast milk and should be avoided in most cases.
Driving Safe This medicine should not impact your ability to drive, but if you experience side effects, take caution.
Sun exposure Caution This medicine can increase sensitivity to sunlight, increasing the risk of sunburn. Wear protective clothing and sunscreen if going out when it’s sunny.

How should I store Doxycycline?

To safely store your capsules, follow these guidelines:

  • Store below 25°C in the original packaging
  • Do not use this medicine after the expiry date
  • Keep this medicine out of the sight and reach of children
  • Do not throw away medicines via wastewater or household waste.*

*Take any unused medication to your local pharmacy for proper disposal. These measures help to protect the environment.

Can I buy Doxycycline without a prescription?

No, this is a prescription-only medication. You need a valid prescription from a healthcare professional to purchase it. This ensures the medication is safe and suitable for your needs.

You can receive an online prescription from euroClinix.

How can I buy Doxycycline online from euroClinix?

Ordering Doxycycline online from euroClinix is convenient.

Follow these simple steps:

  1. Complete a quick online consultation to check your eligibility.
  2. UK-registered doctors review your responses to ensure the medication is right for you.
  3. Upon approval, an e-prescription will be issued.
  4. Enjoy free delivery from our licensed pharmacy with tracking details.

Your privacy is our top priority. euroClinix uses secure, encrypted transactions and complies with UK medical standards to keep your information confidential.

Start your online consultation today to enjoy professional care from the comfort of your home.

Why should I choose euroClinix?

euroClinix is trusted by thousands of users in the UK for its safe and convenient service. Here’s why:

  • Experienced doctors manage your consultations and prescriptions.
  • Online consultations, quick approvals, and discreet doorstep delivery add to the convenience.
  • A supportive team is on hand to answer treatment-related questions or concerns.
  • Patients can manage their prescriptions hassle-free through our secure platform.

Join thousands who trust euroClinix for their healthcare needs and take control of your health today.

How much does Doxycycline cost?

The price of Doxycycline at euroClinix includes everything you need:

  • Free online consultation with our experienced doctors
  • Free prescription, if approved
  • Free delivery straight to your door

Our pricing is transparent, with no hidden fees. Order today and benefit from our complete, all-inclusive service.

What alternatives are available?

For ureaplasma urealyticum and non-specific urethritis, only Doxycycline is available, but there are other options for treating chlamydia or preventing malaria.

Condition Medication Typical dosage Key advantages Key disadvantages Price
Chlamydia Doxycycline 100 mg twice daily for 7-10 days Lower cost, well studied Cannot be used during pregnancy, can cause sun sensitivity -
Azithromycin 1 g single dose Single dose, safe for pregnant women Higher cost, gastrointestinal side effects -
Malaria prevention Doxycycline 100 mg daily, starting 1-2 days before travelling and ending 4 weeks after Lower cost, also treats other infections Daily dosing, can cause sun sensitivity, long-lasting treatment -
Malarone 250 mg/100 mg daily, starting 1-2 days before travelling and ending 7 days after Side effects are less common, shorter treatment course Higher cost, limited safety data for pregnancy -

Once you have decided on a treatment, simply fill out a consultation form and you can start getting better as soon as possible.

Doxycycline vs Azithromycin

Where Doxycycline is a tetracycline antibiotic, Azithromycin is a macrolide antibiotic. These medications target a different part of bacteria cells than tetracyclines, but produce roughly the same effect.

While both treatments are effective, they work in slightly different ways and can produce different side effects. Azithromycin is only prescribed if there is a reason why you cannot take doxycycline, for example if you are allergic to doxycycline, or if you are pregnant or breastfeeding.

Doxycycline Capsules FAQs

Can you drink alcohol with Doxycycline?
How long after taking Doxycycline can I drink alcohol?
Is Doxycycline a penicillin?
Does Doxycycline make you tired?
How long do Doxycycline side effects last?
Can Doxycycline make you sick?
Can you take paracetamol with Doxycycline?
Are there any discounts for being a new user?
Is it safe to buy Doxycycline online?
Will my order be confidential?
What are the delivery options available?

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Medically reviewed by Dr. Caroline Fontana Written by our editorial team Last reviewed 18-02-2025
Doxycycline Capsules information
Type of medicine Tetracycline antibiotic
Used for Treatment of various STIs, acne, and malaria
Active ingredient(s) Doxycycline hyclate
Works by Stopping bacteria from reproducing
Effective within Chlamydia - 7 days
Acne - 6-12 weeks
Syphilis - 2 weeks
Available as Capsules
Available dosage(s) 100 mg
Usage instructions STIs - 100 mg twice daily for 7-10 days
Malaria - 200 mg daily for at least 7 days
Packaging Blister packs
Manufacturer Various
Branded available? No
Storage Store below 25°C in the original packaging. Protect from moisture and direct heat
Prescription required? Yes, get it with our FREE online consultation
Who is suitable for an online consultation* Men and women over 18 with malaria or certain STIs

*Note: Our medical team must review your online consultation before approving this treatment. They will determine if the requested treatment and quantity are safe, appropriate, and effective for you.

Doxycycline Capsules reviews
Package of Doxycycline 100mg contains 8 capsules Excellent 4.7 207 patients have reviewed Doxycycline Capsules on Trustpilot
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