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Dermovate Cream and Ointment

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What is Dermovate?

Dermovate is a strong steroid treatment that helps reduce inflammation, redness, and itching in severe skin conditions, such as psoriasis and eczema. It works by suppressing the immune response that causes flare-ups, making it effective for short-term use in difficult-to-treat cases.

Manufactured by GlaxoSmithKline, it was first approved for use in the UK in March 1993. Since then, it has become one of the most effective and fast-acting prescription treatments for severe skin conditions, offering rapid relief from symptoms like itching and redness.

At euroClinix, we prescribe Dermovate cream or ointment specifically for psoriasis and eczema. Since it is a powerful treatment, it should be used for no longer than 4 weeks unless your doctor has told you otherwise.

What are Dermovate cream and ointment used for?

Dermovate in both forms is most commonly used for short-term treatment of severe cases of eczema or psoriasis. It can also be used for other severe skin conditions, or for stubborn dermatitis that has not responded to milder treatments.

Which one should I use?

  • Use Dermovate cream if your skin is moist or weeping
  • Use Dermovate ointment if your skin is dry, scaly, or thickened

If you are unsure which one is right for you, consult a doctor for personalised advice.

How does Dermovate work?

Dermovate works by reducing inflammation and helping to relieve symptoms like redness, swelling, and itching.

Its active ingredient, clobetasol propionate, is a powerful corticosteroid that calms the immune system and constricts blood vessels. This helps control flare-ups and prevents further irritation.

Symptoms should improve with regular use, leaving your skin smoother and healthier within weeks.

What are the benefits of Dermovate?

Using Dermovate to treat your skin condition provides several benefits.

Key benefits of Dermovate

Image 1

Fast-acting relief from inflammation

Targets inflammation directly, reducing redness, swelling, and irritation within a few days.

Image 2

Quick and long-lasting symptom relief

Most notice improvement within days, with skin healing completely within 2-4 weeks when used consistently.

Image 3

Soothes itchy, irritated skin

Breaks the itch-scratch cycle, providing instant relief and preventing further skin damage.

Image 4

Effective against stubborn skin conditions

Clinically proven to treat eczema, psoriasis, and other severe skin conditions where milder treatments have been ineffective.

Image 5

Powerful, trusted treatment

one of the strongest corticosteroids available, ensuring fast and effective treatment.

How effective is Dermovate?

Dermovate is one of the most effective eczema and psoriasis treatments available. Its potent formulation reduces symptoms fast, with most patients seeing visible improvement within days.

Before and after Dermovate use

One clinical trial involving 58 patients compared Clobetasol propionate (the active ingredient of Dermovate) to Mometasone furoate as a treatment for eczema. The results showed that:

  • Clobetasol was 3.5 times more effective than Mometasone furoate
  • 70% of patients experienced significant skin improvement after 3 weeks

Clinical effectiveness of Dermovate

Patients showing significant improvement in their condition

70%+

Dermovate

(Clobetasol 0.05% cream)

VS

20%+

Mometasone

(Mometasone 0.1% cream)

Dermovate demonstrated a 3.5 times higher improvement rate in eczema patients

A separate trial has found Clobetasol propionate to be similarly effective when treating psoriasis.

In this trial, Clobetasol propionate demonstrated superior effectiveness over Betamethasone (an alternative treatment) in reducing redness, scaling, and skin thickness, proving it to be a versatile and effective treatment.

Who can and cannot use Dermovate?

This medication is not suitable for everyone. When you complete a consultation, our UK-registered doctors will be able to determine if Dermovate is safe for you.

Who can use it?

At euroClinix, we prescribe Dermovate to adults with severe eczema or psoriasis.

Who cannot use it?

You cannot use this medicine if:

  • You are allergic to clobetasol propionate or any other ingredient
  • You are treating the following conditions:
    • Acne
    • Rosacea
    • Rash of the mouth
    • Itching around your anus or genitals
    • Infected skin
    • Itchy skin that isn’t inflamed
    • Widespread plaque psoriasis (raised, dry patches)

Cautions

Consult with your doctor before use if you:

  • Use other oral or topical corticosteroids
  • Experience newly developed bone pain
  • Have previously had an allergic reaction to another steroid
  • Are planning to apply the medicine to broken or damaged skin or skin folds
  • Are applying near eyes or eyelids
  • Are applying to thin skin
  • Are applying it near a chronic leg ulcer

Please disclose your health status during your online consultation with euroClinix. Our doctors will evaluate whether treatment is suitable for you and may adjust your medications if needed.

How do I use Dermovate?

To use this medicine correctly, follow the dosage and treatment course our medical team prescribes. This ensures the drug's effectiveness and helps avoid side effects.

Dosage

The usual recommended dosage is a thin layer applied 1-2 times daily to the affected area until your symptoms disappear. Once symptoms subside, gradually discontinue treatment, as suddenly stopping can risk symptoms coming back

This is a strong steroid treatment. Do not use it for longer than 4 weeks unless instructed to by your doctor.

How much should I use?

How much you use depends on the size of the affected area of the skin. Use enough so that a thin layer of your cream or ointment covers the entire area.

If you are unsure, you can measure the cream or ointment in fingertips. Here are the general guidelines for how much to use:

Face and neck 2½ fingertips
Back 7 fingertips
Front 7 fingertips
Arm (not including the hand) 3 fingertips
Both sides of a hand 1 fingertip
Leg (not including the foot) 6 fingertips
Foot 2 fingertips

This is only a general guide. It’s okay to use more or less when needed.

How do I apply Dermovate?

How to apply the cream and the ointment
how-to-use1

Wash your hands before applying the product

how-to-use2

Apply a thin layer to the affected area and rub it in gently

how-to-use3

Wait until it is fully absorbed before getting dressed

If you have thick patches of psoriasis on your elbows or knees, your doctor may suggest applying the cream under an airtight dressing when you first begin treatment. After a brief time, you can then apply it as normal.

When should I use it?

If applying once a day, pick a time that works best for you and consistently use it at that time every day.

If applying twice a day, try to leave a gap of 8-12 hours between applications.

What if I miss a dose?

If you forget to apply your cream or ointment, use it as soon as you remember and continue to use it regularly. Do not apply more to make up for a missed dose; apply a thin layer as usual.

How long does Dermovate take to work?

Your skin should improve within a few days, but it can take 2-4 weeks for symptoms to resolve fully.

If your condition doesn’t improve or gets worse within this time, consult your doctor for advice.

What should I do while using Dermovate?

To ensure treatment is as effective as possible, implement the following things into your routine when using Dermovate.

Your Dermovate treatment guide

Image 1

Avoid other creams/ointments

Using other products can interfere with Dermovate’s effectiveness.

Image 2

No tight dressings

Don’t cover the area unless told to do so by your doctor, as this can increase the risk of side effects.

Image 3

Monitor sensitive areas

Avoid use in sensitive areas, such as face and private parts, unless instructed otherwise.

Image 4

Avoid smoking and naked flames

Fabric in contact with Dermovate catches fire more easily and risks burns.

Image 5

Avoid triggers

Stay away from things that can worsen your condition, e.g. stress.

Image 6

Make dietary changes

Include anti-inflammatory foods in your diet.

To improve skin health, incorporate anti-inflammatory foods like omega-3-rich fish and brightly-coloured fruits into your diet while steering clear of refined sugars, alcohol, and allergens that may provoke flare-ups such as gluten and dairy.

Silvia Fonda Nutritionist

What are the Dermovate side effects?

Dermovate cream side effects are mostly mild and should go away within a few days of use. Short-term use is unlikely to cause serious side effects, however, using it for a long time can increase the risk of side effects drastically.

Overusing very potent corticosteroids like Dermovate can cause skin thinning, stretch marks, and adrenal gland problems, and stopping treatment suddenly can cause steroid withdrawal, which risks symptoms worsening.

Report any side effects you experience to your doctor, including the following:

Common side effects

The following may affect up to 1 in 10 people:
  • A feeling of burning, pain, irritation or itching at the application site

Uncommon side effects

The following may affect up to 1 in 100 people:
  • Skin thinning (may cause stretch marks)
  • Blood vessels under the skin becoming more noticeable

Very rare side effects

The following are associated with long-term use, and may affect up to 1 in 10,000 people:
  • Weight gain
  • Rounding of the face
  • Obesity
  • Skin wrinkling
  • Skin dryness
  • Changes to the colour of your skin
  • Increased body hair
  • Hair loss

Consult your doctor if you experience blurred vision or other visual disturbances.

Only a thin layer of cream or ointment is needed to effectively treat your condition, and this will reduce the risk of side effects. If side effects persist, talk to your doctor about switching to a milder treatment.

Dr. Caroline Fontana Lead Prescribing Doctor

For more detailed information, please refer to the patient information leaflet.

What interacts with Dermovate?

Most other medicines can be taken alongside Dermovate, but some may affect how it works or increase the risk of side effects. Avoid medicines that inhibit an enzyme called CYP3A4, as these can impact the effectiveness of this drug.

Tell your doctor about any other medicine you take, including:

  • HIV medications (e.g., ritonavir, cobicistat)
  • Antifungal medications (e.g., itraconazole, ketoconazole)
  • Other steroidal treatments (e.g., steroid tablets, asthma inhalers, nasal sprays)

This list does not cover all possible interactions. For a comprehensive list, please visit the interactions checker on Drugs.com.

What safety advice should be followed while using Dermovate?

Category Safety Advice
Alcohol Caution Excessive alcohol consumption can impair skin healing and exacerbate your skin condition. Limit your drinking during treatment.
Pregnancy Consult your doctor The safety of Dermovate during pregnancy has not been properly established. Consult your doctor before use.
Breastfeeding Caution Do not apply Dermovate to your breast area if breastfeeding to ensure your baby does not get it in their mouth.
Driving Safe Dermovate should not impair your ability to drive, but you should monitor how it affects you before driving.
Sun exposure Avoid Dermovate can increase skin sensitivity, making you more susceptible to sunburn. Avoid direct sunlight on the affected areas.

How should I store Dermovate?

Dermovate cream

Follow these guidelines when storing the cream:

  • Store below 25°C in the original packaging
  • Keep this medicine out of the sight and reach of children
  • Do not use this medicine after the expiry date

Dermovate ointment

The guidelines for storing the ointment are the same as for the cream, except for the temperature. Dermovate ointment should be stored below 30°C in the original packaging.

Disposal

Do not throw away medicines via wastewater or household waste.

Take any unused medication to your local pharmacy for proper disposal. These measures help to protect the environment.

Can I buy Dermovate without a prescription?

No, you cannot buy Dermovate over the counter. This medication can only be obtained with a prescription from a licensed healthcare provider.

Prescriptions are necessary because they:

  • Ensure appropriate use for your specific condition.
  • Prevent potential misuse and associated health risks.
  • Allow for monitoring of side effects and interactions with other medications.

How do I buy Dermovate online from euroClinix?

Ordering Dermovate online from euroClinix is convenient.

Follow these simple steps:

  1. Complete a quick online consultation to check your eligibility.
  2. UK-registered doctors review your responses to ensure the medication is right for you.
  3. Upon approval, an e-prescription will be issued.
  4. Enjoy free delivery from our licensed pharmacy with tracking details.

Your privacy is our top priority. euroClinix uses secure, encrypted transactions and complies with UK medical standards to keep your information confidential.

Start your online consultation today to enjoy professional care from the comfort of your home.

Why should I choose euroClinix?

euroClinix is trusted by thousands of users in the UK for its safe and convenient service. Here’s why:

  • Experienced doctors manage your consultations and prescriptions.
  • Online consultations, swift approvals, and discreet doorstep delivery make ordering quick and convenient.
  • A supportive team is on hand to answer treatment-related questions or concerns.
  • Patients can manage their prescriptions hassle-free through our secure platform.

How much does Dermovate cost?

The price of Dermovate at euroClinix includes everything you need:

  • Free online consultation with our experienced doctors
  • Free prescription, if approved
  • Free delivery straight to your door

Our pricing is transparent, with no hidden fees. Order today and benefit from our complete, all-inclusive service.

What alternatives are available?

If Dermovate isn’t right for you, other treatments at euroClinix might be better suited to your needs.

Comparison of psoriasis & eczema treatments
Choose what to compare:
Medication Strength Form Used for How to apply Key advantages Best for Price
Dermovate Very potent Cream, ointment, scalp application Psoriasis, eczema, dermatitis, certain skin diseases 1-2 times daily for up to 4 weeks Strongest treatment with rapid anti-inflammatory action Short-term management of severe conditions -
Betnovate Potent Cream, ointment, lotion, scalp application Psoriasis, eczema, dermatitis 1-2 times daily until symptoms subside Generally well-tolerated and effective Acute flare-ups and moderate conditions -
Elocon Potent Cream, ointment, scalp application Psoriasis, eczema, dermatitis 1 time daily until symptoms subside Effective and generally safe option Long-term management of skin conditions -
Locoid Moderately potent Cream, ointment, scalp application Psoriasis, eczema, dermatitis 1-2 times daily until symptoms subside Lower risk of skin thinning Chronic conditions and delicate skin (face, skin folds) -

Dermovate FAQs

Can I use Dermovate on my private parts?
Is Dermovate stronger than Betnovate?
Can I use Dermovate on my pimples?
Can Dermovate be used for fungal infections?
Can Dermovate be used on the face?
Can you use Dermovate on broken skin?
Is Dermovate a steroid cream?
Are there any discounts for being a new user?
Is it safe to buy Dermovate online?
Will my order be confidential?
What are the delivery options available?

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Medically reviewed by Dr. Caroline Fontana Written by our editorial team Last reviewed 03-04-2025
Dermovate information
Type of medicine Corticosteroid
Used for Severe psoriasis, eczema or dermatitis
Active ingredient(s) Clobetasol propionate
Works by Reducing swelling and inflammation in the skin
Effective within 2-4 weeks
Available as Cream and ointment
Available dosage(s) 0.05% clobetasol
Usage instructions Apply a thin layer to the skin 1-2 times daily for up to 4 weeks
Packaging A 30 g or 100 g tube
Manufacturer GlaxoSmithKline
Generic available? No
Storage Store below 25°C in its original packaging
Protect from direct heat and moisture
Prescription required? Yes, get one with our FREE online consultation
Who is suitable for an online consultation* Adults with psoriasis or eczema

*Note: Our medical team must review your online consultation before approving this treatment. They will determine if the requested treatment and quantity are safe, appropriate, and effective for you.

Dermovate reviews
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Further reading

Understanding and managing the side effects of corticosteroids

Understanding and managing the side effects of corticoste...

Reviewed by Dr. Caroline Fontana
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